The Kick-off Symposium of Advanced Graduate Program for Future Medicine and Health Care
(The symposium has ended. Thank you for your participation.)
Poster Presentation and Discussion
YSOS1-1/PS
Analysis of the CDKN2A gene in FAMMM Syndrome families reveals early age of onset for additional syndromic cancers
Candace D. Middlebrooks1, Mark Stacey2, Qing Li1, Carrie Snyder2, Trudy Shaw2, Marc Rendell3, Claire Ferguson2, Theresa Townley4, Peter Silberstein5, Murray Joseph Casey2,6, Stephen Lanspa7, Joan E. Bailey-Wilson1, Henry T. Lynch2 (1Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD, 2Hereditary Cancer Center, Creighton University, Omaha, NE, 3The Rose Salter Medical Research Foundation, Newport Coast, CA, 4Internal Medicine Department, Creighton University, Omaha, NE, 5Department of Hematology/Oncology, Creighton University, Omaha, NE, 6Department of Obstetrics and Gynecology, Creighton University, Omaha, NE, 7Internal Medicine Department - Gastrointestinal Division, Creighton University, Omaha, NE)
YSOS1-2/PS
Pathways of Progression from Intraductal Papillary Mucinous Neoplasm to Pancreatic Ductal Adenocarcinoma Based on Molecular Features
Omori Y1,2,3, Ono Y4,5, Tanino M2, Karasaki H4, Yamaguchi H6, Furukawa T1, Enomoto K5, Ueda J7, Sumi A4, Katayama J8, Muraki M9, Taniue K4,9, Takahashi K9, Ambo Y10, Shinohara T3, Nishihara H11, Sasajima J4,5, Maguchi H9, Mizukami Y4,5, Okumura T5, Tanaka S2 (1Department of Histopathology, Tohoku University Graduate School of Medicine, 2Department of Cancer Pathology, Hokkaido University Graduate School of Medicine, 3Department of Pathology, Teine-Keijinkai Hospital, 4Institute of Biomedical Research, Sapporo Higashi Tokushukai Hospital, 5Department of Medicine, Asahikawa Medical University, 6Division of Diagnostic Pathology, Tokyo Medical University, 7Center for Advanced Research and Education, Asahikawa Medical University, 8Diagnostic Partnering, Clinical Sequencing Division, Thermo Fisher Scientific, 9Center for Gastroenterology, Teine-Keijinkai Hospital, 10Department of Surgery, Teine-Keijinkai Hospital, 11Cancer Center, Keio University Hospital)
YSOS1-3/PS
The mitochondria gain-of-function phenotype in oncogenic Ras-driven metastatic breast cancer
May Yin Lee1, Yanzhe Li1, Jason Tham1, Esther Peh2, Ying Swan Ho2, Salanne Lee3, Kah Min Ang3, Ivy Low3, Siming Ma1, Cheryl Phua1, Edwin Lim1, Wai Leong Tam1,4 (1Genome Institute of Singapore, A*STAR, 2Bioprocessing Technology Institute, A*STAR, 3Flow Cytometry Core, Singapore Immunology Network, A*STAR, 4Cancer Science Institute, Singapore)
YSOS1-4/PS
Regulation of chromatin dynamics and autophagy by non-histone chromatin protein PC4: Implications in Breast cancer
Sweta Sikder1, Sujata Kumari1, Manoj Kumar1, Srikumar Chellapan2, K.S. Gopinath3, Ravi Manjithaya4, Tapas K Kundu1 (1Transcription and Disease laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, India, 2Department of Tumour Biology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, 3Bangalore Institute of Oncology, Bangalore, India, 4Autophagy Laboratory, Molecular Biology and Genetics Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, Karnataka, India)
YSOS1-5/PS
Quantifying transcription at Single Molecule level reveals linked cycles of chromatin remodeling and transcription factor binding at gene promoter
Gunjan Mehta1, David Ball1, James McNally2, Tatiana Karpova1 (1CCR/LRBGE Optical Microscopy Core, National Cancer Institute, National Institutes of Health, Bethesda, MD, 2Institute for Soft Matter and Functional Materials, Helmholtz Center Berlin, Berlin, Germany)
YSOS1-6/PS
A novel machinery for maintenance of faithful chromosome segregation
Kenji Iemura, Kozo Tanaka (Department of Molecular Oncology, Institute of Development, Aging and Cancer, Tohoku University)
YSOS2-1/PS
In vitro and in vivo knock-out system labelled by fluorescent protein via microhomology-mediated end joining
Shota Katayama1,2, Kota Sato2,3, Toru Nakazawa1,2,3,4 (1Department of Advanced Ophthalmic Medicine, Tohoku University Graduate School of Medicine, 2Department of Ophthalmology, Tohoku University Graduate School of Medicine, 3Department of Ophthalmic Imaging and Information Analytics, Tohoku University Graduate School of Medicine, 4Department of Retinal Disease Control, Tohoku University Graduate School of Medicine)
YSOS2-2/PS
Categorizing Autism Spectrum Disorder Candidate Genes
Victoria Heigh, Harold Burgess (Section on Behavioral Neurogenetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development)
YSOS2-3/PS
Multifunctional fibers for elucidating astroglial basis of anxiety
Yuanyuan Guo, Ko Matsui (Frontier Research Institute of Interdisciplinary Sciences; Department of Super-network Brain Physiology, Graduate School of Life Sciences; Department of Physiology, Tohoku University School of Medicine)
YSOS2-4/PS
Association of Amyloid Positivity with Volume Loss in Temporal Lobes Differs between Men and Women in Cognitively Normal Older Adults
Nicole M. Armstrong1, Chiung-Wei Huang1, Owen Williams1, Murat Bilgel1, Yang An1, Jimit Doshi2, Guray Erus2, Christos Davatzikos2, Dean F. Wong3, Luigi Ferrucci1, Susan Resnick1 (1National Institute on Aging Intramural Research Program, National Institutes of Health, Baltimore, MD, 2Section of Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, Philadelphia, PA, 3Section of High Resolution Brain PET, Departments of Neurology, Psychiatry, Neuroscience, and Radiology, Johns Hopkins University School of Medicine, Baltimore, MD)
YSOS2-5/PS
Structural biology of β-sheet ligand-type PET probes and monoamine oxidase
Ryuichi Harada1,2, Yoshikazu Tanaka3, Shozo Furumoto4, Kazutaka Murayama5, Takeo Yoshikawa1, Ren Iwata4, Yukitsuka Kudo2, Nobuyuki Okamura6, Hiroyuki Arai2, Kazuhiko Yanai1 (1Department of Pharmacology, Tohoku University Graduate School of Medicine, 2Department of Geriatrics and Gerontology, Division of Brain Science, Institute of Development, Aging and Cancer, Tohoku University, 3Department of Applied Biological Molecular Science, Tohoku University Graduate School of Life Sciences, 4Cyclotron Radioisotope Center, Tohoku University, 5Department of Biomedical Engineering, Biomedical Measurements and Diagnostics Biomedical Supramolecular Analysis, Tohoku University Graduate School of Bioengineering, 6Division of Pharmacology, Tohoku Medical and Pharmaceutical University)
YSOS2-6/PS
Interactions of synthetic cannabinoids with the 5HT1A receptor
Hideaki Yano, Ravi K. Verma, Sett Naing, Pramisha Adhikari, Alexander F. Hoffman, Michael H. Baumann, Carl R. Lupica, Lei Shi (National Institute on Drug Abuse, National Institutes of Health)
YSOS2-7/PS
A Novel Allosteric Drug That Stimulates Insulin Secretion by Acting on β-Cell M3 Muscarinic Acetylcholine Receptors
Jonathan Pham, Lu Zhu, Mario Rossi, Hongchao Zheng, Jennifer L. Langel, Samer Hattar, Daniel Appella, Nicolai M. Doliba, Jürgen Wess (Molecular Signaling Section, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD)
YSOS3-1/PS
Surprise at tissue-resident macrophages in development: brain-resident macrophages control radial glia and cortex development
Chang Liu, Yoh-suke Mukouyama (Laboratory of Stem Cell and Neuro-Vascular Biology, Cell and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health)
YSOS3-2/PS
How TLR9 Signaling shapes the survival, differentiation and the metabolism of B cells
Munir Akkaya1, Billur Akkaya1, Alexander Roesler1, Pietro Miozzo1, Brandon Theall1, Javier Traba2, Mirna Pena1, Susan Pierce1 (1National Institutes of Allergy and Infectious Diseases, Rockville MD, 2National Heart Lung, Blood Institute, Bethesda, MD)
YSOS3-3/PS
PRMT5 Modulates Splicing for Genome Integrity and Preserves Proteostasis of Hematopoietic Stem Cells
Darren Qiancheng Tan1, Ying Li1, Chong Yang1, Jia Li1, Shi Hao Tan1, Desmond Wai Loon Chin2, Ayako Nakamura-Ishizu1,3, Henry Yang1, Toshio Suda1,3 (1Cancer Science Institute of Singapore, National University of Singapore, Singapore, 2Department of Medicine, Huddinge, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden, 3International Research Center for Medical Sciences, Kumamoto University, Japan)
YSOS3-4/PS
Identification of the tooth-specific novel transcription factor AmeloD and its role during tooth development
Yuta Chiba, Kan Saito, Takashi Nakamura, Yoshihiko Yamada, Satoshi Fukumoto (Division of Pediatric Dentistry, Department of Oral Health and Development Sciences, Tohoku University Graduate School of Dentistry)
YSOS3-5/PS
The transcription factor Foxc1 is necessary for Ihh–Gli2-regulated endochondral ossification
Michiko Yoshida1,2, Kenji Hata1, Rikako Takashima1, Koichiro Ono1, Eriko Nakamura1, Yoshifumi Takahata1, Tomohiko Murakami1, Itaru Mizoguchi2, Sachiko Iseki3, Teruko Takano-Yamamoto2, Riko Nishimura1, Toshiyuki Yoneda1 (1Department of Molecular and Cellular Biochemistry, Osaka University Graduate School of Dentistry, 2Division of Orthodontics and Dentofacial Orthopedics, Tohoku University Graduate School of Dentistry, 3Section of Molecular Craniofacial Embryology, Graduate School of Medical and Dental Sciences,Tokyo Medical and Dental University)
PS1
Tyrosine kinase receptor TIE-1 serves as a novel therapeutic target in PI3K highly expressing ovarian cancer
Xuewei Zhang, Masumi Ishibashi, Shogo Shigeta, Nobuo Yaegashi (Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine)
PS2
The mechanism of epigenetic regulation by the interaction between nuclear FABP7 and ACLY
Yoshiteru Kagawa, Banlanjo A. Umaru, Yuji Owada (Department of Organ Anatomy, Tohoku University Graduate School of Medicine)
PS3
Cortical processing of prediction error and self-agency in patients with schizophrenia
Koichi Abe, Motoaki Sugiura, Tatsuo Kikuchi, Atsushi Sakuma, Hiroo Matsuoka, Ryuta Kawashima, Kazunori Matsumoto (Department of Human Brain Science, Institute of Development, Aging and Cancer, Tohoku University)
PS4
Chronic poor condition enhances preference to rewarding substances through dopamine system
Toshiharu Ichinose1,2, Mai Kanno2, Shu Kondo3, Sena Hatori1, Riho Kobayashi1, Shun Hiramatsu2, Ayako Abe2, Kazuhiko Kume1, Hiromu Tanimoto2 (1Departoment of Neuropharmacology, Nagoya City University, 2Laboratory of Neuroethology, Graduate School of Life Sciences, Tohoku University, 3 National Institute of Genetics, Mishima, Japan)
PS5
The involvement of fatty acid-binding protein 5 in the blood-brain barrier transport of docosahexaenoic acid and cognition
Yijun Pan1, Joseph Nicolazzo2, Yuji Owada1 (1Department of Organ Anatomy, Tohoku University Graduate School of Medicine, 2Pharmacy and Pharmaceutical Science, Monash University)
PS6
The effect of UGT1A9, CYP2B6, CYP2C9 genes polymorphism on individual differences in propofol pharmacokinetics among Japanese patients
Akihiro Kanaya, Nobuo Fuse, Masanori Yamauchi (Department of Anesthesiology and Perioperative Medicine, Tohoku University School of Medicine)
PS7
Blood Pressure Correlates with 90-Day Mortality in Sepsis Patients: A Retrospective Multicenter Derivation and Validation Study Using High-Frequency Continuous Data
Naoya Kobayashi, Atsuhiro Nakagawa, Daisuke Kudo, Tsukasa Ishigaki, Haruya Ishizuka, Kohji Saito, Yutaka Ejima, Toshihiro Wagatsuma, Hiroaki Toyama, Kuniyasu Niizuma, Shigeki Kushimoto, Teiji Tominaga, Masanori Yamauchi (Department of Anesthesiology and Perioperative Medicine, Tohoku University Graduate School of Medicine)
PS8
Functions of a cancer/testis antigen gene, Tekt5 in cancer cells and male germ cells
Nana Aoki, Yasuhisa Matsui (Cell Resource Center for Biomedical Research, Institute of Development, Aging and Cancer, Tohoku University)