Dates:

March 5th (Tue) -7th (Thu), 2019

Venue:

Seiryo Auditorium, Tohoku University
2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan
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Program:

March 5 (Tue)

9:30-10:00	Opening Session ・Opening Remarks: Keiko Nakayama (Tohoku University, Japan) ・Opening Address: Hiroo Yugami (Tohoku University, Japan)
10:00-12:00	Special Session: Advanced Graduate Program in Future Medicine 　Chair: Nobuhiro Takahashi (Tohoku University, Japan) ・Christopher Peck (University of Sydney, Australia) “Improving health and wellbeing through co-design: the Westmead Living Lab” ・Jianmin Han (Peking University School and Hospital of Stomatology, China) “Chinese medical device regulation update” ・Wataru Uchida (Tohoku University, Japan) “Aiming for future medicine and healthcare: Tohoku University open innovation”
13:00-13:50	Plenary Lecture 　Chair: Hozumi Motohashi (Tohoku University, Japan) ・Yoshiaki Ito (National University of Singapore, Singapore) “Roles of RUNX genes in tissue stem cells”
14:00-15:35	Scientific Session 1: Inflammation and Immune Response 　Chair: Akihiko Muto (Tohoku University, Japan) ・Junken Aoki (Tohoku University, Japan) “Lipidomics revealed a novel role of omega-3-containing lysophospholipid in activating vagal nerve via LPA3 receptor to protect heart from ischemic damage” ・Johan Garaude (INSERM U1211, France) “Regulation of mitochondrial respiratory chain by innate immunity” ・Takehiko Yokomizo (Juntendo University, Japan) “The roles of leukotriene B4 receptor in macrophage and dendritic cell”
15:50-17:30	Scientific Session 2: Redox Biology 1 　Chair: Norio Suzuki (Tohoku University, Japan) ・James R. Mitchell (Harvard School of Public Health, USA) “Hydrogen sulfide in oxidative stress resistance, metabolic fitness and longevity” ・Takaaki Akaike (Tohoku University, Japan) “Cysteine persulfide synthases mediate sulfur respiration and energy metabolism” ・Yvonne Janssen-Heininger (University of Vermont, USA) “Causal role for glutathione-induced protein oxidation in tissue fibrosis: new avenues for redox-based therapeutics?”
17:40-19:30	Poster Presentation and Discussion [more]

March 6 (Wed)

9:00-10:30	Scientific Session 3: Redox Biology 2 　Chair: Atsushi Matsuzawa (Tohoku University, Japan) ・Masayuki Yamamoto (Tohoku University, Japan) “KEAP1-NRF2 system and its future” ・Hiroaki Miki (Osaka University, Japan) “Regulation of Mg2+ levels and ROS generation by PRL/CNNM protein complexes” ・Yoshiaki Kubota (Keio University, Japan) “Intrinsic mechanism for separating blood and lymphatic vascular systems in development and cancer”
10:40-12:20	Scientific Session 4: Neuroscience 　Chair: Hiromu Tanimoto (Tohoku University, Japan) ・Luca Peruzzotti-Jametti (University of Cambridge, UK) “Targeting the metabolism of innate immune cells as a therapeutic strategy for progressive multiple sclerosis” ・Ken-Ichiro Tsutsui (Tohoku University, Japan) “Trans-cranial magnetic stimulation (TMS): a powerful tool for neuromodulation and functional mapping of the cerebral cortex” ・Martin A. Giese (University of Tuebingen, Germany) “Computational approaches in action vision and control and implications in basic and clinical research”
13:00-14:30	Young Scientists Oral Session 1: Oncology & Chromosome ・Candace Middlebrooks (NHGRI, NIH, USA) “Analysis of the CDKN2A gene in FAMMM syndrome families reveals early age of onset for additional syndromic cancers” ・Yuko Omori (Tohoku University, Japan) “Pathways of progression from intraductal papillary mucinous neoplasm to pancreatic ductal adenocarcinoma based on molecular features” ・May Yin Lee (Genome Institute of Singapore, NUS, Singapore) “The mitochondria gain-of-function phenotype in oncogenic Ras-driven metastatic breast cancer” ・Sweta Sikder (JNCASR, India) “Regulation of chromatin dynamics and autophagy by non-histone chromatin protein PC4: implications in breast cancer” ・Gunjan Mehta (NCI, NIH, USA) “Quantifying transcription at single molecule level reveals linked cycles of chromatin remodeling and transcription factor binding at gene promoter” ・Kenji Iemura (Tohoku University, Japan) “A novel machinery for maintenance of faithful chromosome segregation”
14:40-16:15	Young Scientists Oral Session 2: Neuroscience & Pharmacology ・Shota Katayama (Tohoku University, Japan) “In vitro and in vivo knock-out system labelled by fluorescent protein via microhomology-mediated end joining” ・Victoria Heigh (NICHD, NIH, USA) “Categorizing autism spectrum disorder candidate genes” ・Yuanyuan Guo (Tohoku University, Japan) “Multifunctional fibers for elucidating astroglial basis of anxiety” ・Nicole Armstrong (NIA, NIH, USA) “Association of amyloid positivity with volume loss in temporal lobes differs between men and women in cognitively normal older adults” ・Ryuichi Harada (Tohoku University, Japan) “Structural biology of β-sheet ligand-type PET probes and monoamine oxidase” ・Hideaki Yano (NIDA, NIH, USA) “Interactions of synthetic cannabinoids with the 5HT1A receptor” ・Jonathan Pham (NIDDK, NIH, USA) “A novel allosteric drug that stimulates insulin secretion by acting on β-cell M3 muscarinic acetylcholine receptors”
16:25-17:40	Young Scientists Oral Session 3: Stem Cell & Differentiation ・Chang Liu (NHLBI, NIH, USA) “Surprise at tissue-resident macrophages in development: brain-resident macrophages control radial glia and cortex development” ・Munir Akkaya (NIAID, NIH, USA) “How TLR9 signaling shapes the survival, differentiation and the metabolism of B cells” ・Darren Qiancheng Tan (Cancer Science Institute of Singapore, NUS, Singapore) “PRMT5 modulates splicing for genome integrity and preserves proteostasis of hematopoietic stem cells” ・Yuta Chiba (Tohoku University, Japan) “Identification of the tooth-specific novel transcription factor AmeloD and its role during tooth development” ・Michiko Yoshida (Tohoku University, Japan) “The transcription factor Foxc1 is necessary for Ihh–Gli2-regulated endochondral ossification”
17:45-19:15	Workshop on Global Career Development in Future Medicine

March 7 (Thu)

9:00-10:40	Scientific Session 5: Epigenetic Regulation 　Chair: Yasuhisa Matsui (Tohoku University, Japan) ・Tapas Kumar Kundu (JNCASR, India) “Master epigenetic enzyme p300 in life and death” ・Kazuhiko Igarashi (Tohoku University, Japan) “Gene regulatory network for hematopoietic stem and progenitor cell differentiation” ・Reshma Taneja (National University of Singapore, Singapore) “Identifying epigenetic regulators for targeted therapy in rhabdomyosarcoma”
10:55-12:30	Scientific Session 6: Carcinogenesis 　Chair: Natsuko Chiba (Tohoku University, Japan) ・Susumu Kobayashi (National Cancer Center, Japan) “Resistance to EGFR tyrosine kinase inhibitors” ・Hiroyuki Inuzuka (Tohoku University, Japan) “Regulation of cell survival through post-translational modifications of MCL-1 in tumorigenesis” ・Wenyi Wei (Harvard Medical School, USA) “CRL3/SPOP promotes Nanog destruction to suppress stem cell traits and prostate cancer progression”
12:30-12:40	Closing Session ・Closing Remarks: Kazuhiko Igarashi (Tohoku University, Japan)
13:30-14:30	Tour of Tohoku Medical Megabank Organization (ToMMo) in Tohoku University

Contact:

Advanced Graduate Program for Future Medicine and Health Care, Tohoku University
[E-mail]

Poster:

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